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Cost Effectiveness of Primary Stroke Prevention in Atrial Fibrillation
BMJ 305:1457-1460, 14451992., Gustafsson,C.,et al, 1992
See this aricle in Pubmed

Article Abstract
Depending on the rate of haemorrhagic complications 34 to 83 patients would need to be treated annually with anticoagulants to prevent one stroke;83 patients would need to be treated with aspirin.Giving anticoagulant treatment only would reduce costs by Kr60 million if the incidence of intracranial haemorrhage were 0.3%but would imply a net expense if the complication rate exceeded 1.3%.The total savings from giving anticoagulant(22,000 patients)and aspirin(55,000 patients)treatment would be Krl75 million per year corresponding to 2 million per million inhabitants each year.Treatment with anticoagulants and,if contraindications exist,with aspirin is cost effective provided that the risk of serious haemorrhage complications due to anticoagulants is kept low.
 
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anticoagulant,complications of
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anticoagulant,treatment in CVD
aspirin
atrial fibrillation
cerebrovascular accident
cerebrovascular accident,prevention of
cost effectiveness
coumarin
treatment of neurologic disorder

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